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CYTOCHROME P-450 CYP2B6
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DeCS
Descriptor
English
:
Cytochrome P-450 CYP2B6
Descriptor
Spanish
:
Citocromo P-450 CYP2B6
Descriptor
Portuguese
:
Citocromo P-450 CYP2B6
Tree Number:
D08.244.453.040.575
D08.811.682.690.708.170.040.575
D12.776.422.220.453.040.575
Definition
English
:
A cytochrome P450 enzyme subtype that oxidizes a diverse array of
XENOBIOTICS
. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS. Examples of drugs metabolized by CYP2B6 include
BUPROPION
; efavirenz;
CYCLOPHOSPHAMIDE
; and
MEPERIDINE.
Entry Combination - descr/qualif
English
:
Cytochrome P-450 CYP2B6
/
antagonists & inhibitors
use
Cytochrome P-450 CYP2B6 Inhibitors
History Note
English
:
2015
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55606
Unique Identifier:
D065702
Occurrence in VHL
:
Similar:
DeCS
CID-10
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